Profhilo Bio-remodelling Treatment

Profhilo is not a filler. It does not add volume or reshape features. It is one of the most effective tools available for improving skin quality from within – stimulating collagen and elastin, restoring deep hydration and remodelling the skin’s own architecture in a way that produces a genuinely healthier-looking result.

 

Why skin quality matters

Before addressing lines, volume or contour, the skin itself needs to be in good condition. Profhilo’s role in aesthetic medicine – and within Cosmetica’s approach – is exactly this: improving the baseline quality of the skin so that everything else works better.

Dr Mica Engel has recommended Profhilo as part of her clinical practice for many years. It sits at the core of her regenerative approach alongside Juläine and WOW Fusion – treatments she values because they focus on what the skin is doing from within, not just how it looks from the outside.

Treatment overview

  • Treatment type: hyaluronic acid bio-remodeller (not a filler)
  • Sessions: typically 2, spaced 4 weeks apart
  • Maintenance: one session every 6 months
  • Injection protocol: BAP technique – 5 injection points per side of the face
  • Appointment: 30 minutes
  • Downtime: minimal – small bumps at injection sites resolve within 24–48 hours
  • Areas: face, neck, décolleté, hands – see Profhilo Body for body areas
Treatment overview

How does Profhilo work?

Profhilo contains one of the highest concentrations of pure hyaluronic acid available in an injectable – 64mg per 2ml. Unlike crosslinked dermal fillers, this HA is not designed to hold a fixed position or add volume. Instead, it flows through the tissue and integrates naturally with the skin’s existing structures. Once in the skin, it draws and retains moisture at a deep level. Over the following weeks, it triggers a biological remodelling response – stimulating fibroblasts to produce new collagen and elastin. Clinical studies have shown Profhilo stimulates four types of collagen and elastin, leading to measurable improvements in skin laxity, firmness and overall quality.

What does Profhilo treat?

  • Skin laxity – loss of firmness in the face, neck and décolleté
  • Dull, dehydrated or tired-looking skin
  • Early crepiness or fine texture irregularity
  • Patients wanting to improve overall skin quality before or alongside other treatments
  • Supporting skin health after illness, stress or environmental damage

What to expect

All Profhilo treatments begin with a consultation. The treatment uses the BAP (Bio Aesthetic Points) technique – five precise injection points on each side of the face, allowing the HA to spread evenly. Appointments take approximately 30 minutes. Small bumps at injection points are normal and resolve within 24 to 48 hours. Results are typically noticeable from 2 to 4 weeks after the first session, with optimal results after the second treatment. Maintenance every six months sustains results.

Profhilo and wider skin planning

Profhilo works well alone or as a foundation for a broader plan. It is often combined with anti-wrinkle injections (addressing muscle movement while Profhilo addresses skin quality), with Juläine (additional collagen stimulation and longer-lasting structural support), or with treatments such as the Secret Pro laser for texture, pigmentation or scarring. For body skin laxity, see Profhilo Body.

 

Book your Profhilo consultation or treatment today

Profhilo at Cosmetica London is performed by Dr Mica Engel and Dr Asha Chhaya. Book your treatment today of if unsure if this is the right injectable for you then book a consultation and we will assess your skin, answer your questions and put together a treatment plan for your goals

Frequently Asked Questions

DO YOU HAVE A QUESTION ABOUT THIS TREATMENT? READ OUR FAQS BELOW.